货号：AB9354

品牌：Merck Millipore

规格：500UL

目录价：￥6292.00

市场价格：￥5348.20

会员价格：￥5033.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Beta III Tubulin Antibody | AB9354 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Beta III Tubulin View All» Molecular Weight: 55 kDa View All» Epitope: (Similar to TuJ1 antigen) View All» Immunogen: Synthetic peptides from human/rat Beta III Tubulin. View All» Isotype: IgY View All» Background Information: Tubulins, major components of the cellular cytoskeleton, form microtubules that are critical for cellular structure, migration, cell division, and intracellular trafficking. There are at least three types of tubulins: alpha, beta, and gamma. Each has a molecular weight of approximately 55 kDa. Microtubules are large structures (300 angstrom diameter) composed of alternating alpha and beta subunits. Compounds that block microtuble formation, such as Taxol and the vinca alkaloids, inhibit cell division and are effective anti-cancer agents. Class III β-tubulin‎ is a microtubule element expressed exclusively in neurons, and is a popular marker specific for neurons in tissue. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Immunocytochemistry: 1:1000 - 1:2000 dilution from a previous lot was used in immunocytochemistry using 2% paraformaldehyde fixed cells.Immunohistochemistry: 1:1000 - 1:2000 dilution from a previous lot was used in immunohistochemistry using 2% paraformaldehyde fixed tissues.Optimal working dilutions must be determined by the end user View All» Control: Brain tissue, Neuronal culture View All» Quality Assurance: Routinely evaluated by Western Blot on mouse brain lysates.Western Blot: 1:1000 dilution of this lot detected TUBULIN BETA III on 10 μg of mouse brain lysates. View All» Purification Method: Immunoaffinity purified View All» Presentation: Affinity purified polyclonal chicken IgY liquid in PBS, pH 7.2 with 0.02% sodium azide. Four different antibodies were combined to make this product View All» Storage Conditions: Stable for 6 months at 2-8°C in undiluted aliquots from date of receipt. It is recommended that the antibody be stored in the dark. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. View All» UniProt Number: Q13509 View All» Entrez Gene Number: NM_006086.2 View All» Gene Symbol:
  • TUBB3

  • TUBB4

  • beta-4

  • MC1R
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» UniProt Summary: FUNCTION: SwissProt: Q13509 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.SIZE: 450 amino acids; 50433 Da SUBUNIT: Dimer of alpha and beta chains.DOMAIN:SwissProt: Q13509 The highly acidic C-terminal region may bind cations such as calcium.SIMILARITY: Belongs to the tubulin family. View All» Brand Family: Chemicon View All» Product Name: Anti-Beta III Tubulin Antibody | AB9354 View All» Concentration: 0.4 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 500 µL View All» Target / Localization: All neurons, soma, axons, cytoplasmic, neurites View All» Format: Affinity Purified View All» Host: Chicken View All»
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