货号：AB5691

品牌：Merck Millipore

规格：

目录价：￥4037.00

市场价格：￥3431.45

会员价格：￥3229.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Nucleostemin Antibody | AB5691 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Nucleostemin, mouse. View All» Immunogen: Synthetic peptide from mouse nucleostemin. View All» Background Information: Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle progression in stem cells and cancer cells. View All» Species Reactivity: Mouse View All» Application Notes: Western blot: 1:5,000-1:10,000 using ECL. The antibody reacts with a protein of ~ 63 kDa on MBL-5 cell lysate. Optimal working dilutions must be determined by the end user. View All» Control: MBL-5 cell lysate, E14tG2a (Mouse embryonic stem cell line) whole cell lysate View All» Presentation: Rabbit serum. Liquid. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9BVP2 View All» Entrez Gene Number:

• NM_014366.4

• NM_206825.1

• NM_206826.1
  View All» Gene Symbol:
  • GNL3

  • C77032

  • NS

  • MGC800

  • E2IG3

  • nucleostemin

  • Nucleostemin

  • NNP47
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: Q9BVP2 # May be required to maintain the proliferative capacity of stem cells.SIZE: 549 amino acids; 61997 Da SUBUNIT: May interact with p53/TP53 via its basic domain (By similarity).SUBCELLULAR LOCATION: Nucleus (By similarity). Nucleus, nucleolus (By similarity). Note=Shuttles between the nucleus and nucleolus (By similarity).DOMAIN: SwissProt: Q9BVP2 The basic domain (B) allows nucleolar localization in the absence of GTP. The intermediate domain (I) inhibits nucleolar localization by the B domain and is required for exit from the nucleolus. Exit from the nucleolus to the nucleoplasm requires both the I and the acidic (A) domains, and may be triggered by GTP hydrolysis (By similarity).SIMILARITY: Belongs to the MMR1/HSR1 GTP-binding protein family. View All» Brand Family: Chemicon View All» Product Name: Anti-Nucleostemin Antibody | AB5691 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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