货号：AB5543

品牌：Merck Millipore

规格：50UL

目录价：￥5820.00

市场价格：￥4947.00

会员价格：￥4656.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MAP2 Antibody | AB5543 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Microtubule Associated Protein 2 (MAP2). It is expected that the antibody will react with all mammals. View All» Molecular Weight: Recognizes a doublet of ~280 kDa and a doublet of ~70kDa. View All» Immunogen: Purified bovine brain MAP2 View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:5,000-1:10,000 using ECL. Recognizes a doublet of ~280 kDa and a doublet of ~70kDa. Immunohistochemistry on frozen tissue sections. Suggested fixative is 4% paraformaldehyde (1-10 minutes) followed by 5 minutes in -20°C methanol. Immunocytochemistry: 1:5,000-1:10,000 on cells in tissue culture fixed for 1-10 minutes in 10% formalin followed by five minutes in -20°C methanol. Optimal working dilutions must be determined by the end user. View All» Control: Positive = cerebral cortex. Negative = liver or kidney. View All» Purification Method: Ammonium sulfate precipitation View All» Presentation: Purified chicken IgY. Liquid in PBS containing 5 mM sodium azide. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P11137 View All» Entrez Gene Number:

• NM_001039538.1

• NM_002374.3

• NM_031845.2

• NM_031847.2
  View All» Gene Symbol:
  • MAP2

  • MAP2B

  • MAP-2

  • MAP2C

  • DKFZp686I2148

  • MAP2A
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isforms have been described. View All» UniProt Summary: FUNCTION: SwissProt: P11137 # The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.SIZE: 1827 amino acids; 199539 Da PTM: MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.SIMILARITY: SwissProt: P11137 ## Contains 3 Tau/MAP repeats. View All» Brand Family: Chemicon View All» Product Name: Anti-MAP2 Antibody | AB5543 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μL View All» Target / Localization: All neurons, soma, dendrites View All» Format: Purified View All» Host: Chicken View All»
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