金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TMEFF1/Tomoregulin-1 Long Name: Transmembrane Protein with EFG-like and two Follistatin-like Domains Aliases: C9orf2; Tomoregulin-1 Entrez Gene IDs: 8577 (Human); 230157 (Mouse) Background: TMEFF1 View TMEFF1 IHC images. Transmembrane Protein with EGF-like and two Follistatin-like domains 1 (TMEFF1) also known as tomoregulin-1 is a type I transmembrane glycoprotein. TMEFF1 contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain of TMEFF1 can be released as a soluble protein. TMEFF1 is predominantly expressed in brain, but is downregulated in brain neoplasms. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.