LDN-193189 ALK-2,-3 抑制剂 2mg TGF-beta家族

2023-08-02

产品英文名称:LDN-193189, ALK-2, -3 Inhibitor

产品中文名称:LDN-193189 ALK-2,-3 抑制剂

LDN-193189 产品英文简述:

A selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2 and ALK-3). Only weakly inhibits ALK-4,-5, and -7.

4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline

Ref: Cuny, G.D., et al. Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors. Bioorg Med Chem Lett 18: 4388-92, 2008.

• Purity: Greater than 98% as determined by LC/MS analysis.

• Biological Activity: Not Determined

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