产品英文名称:WNT-3a,Mouse
产品中文名称:鼠重组WNT-3a蛋白
WNT-3a,Mouse 产品介绍:
wnt通路是细胞增殖分化的关键调控环节, 在胚胎发育和肿瘤发生中起着重要作用。wnt途径参与了基因表达调节、 细胞迁移粘附、细胞极化等过程,同时还与其它信号通路存在交叉协同。Wnt/β-catenin通路在进化过程中高度保守,此通路的主要分子构成及相关调控机制已得到基本阐明。对神经系统而言已有足够证据显示此通路参与了对神经前体细胞增殖, 分化以及决定细胞命运的调控。
Wnt-3a是Wnt基因家族中重要成员,最近的一些研究发现, Wnt-3a信号蛋白对神经干细胞的定向分化的调控作用表现的十分明显。小鼠WNT-3a蛋白包含328个氨基酸。
WNT-3a,Mouse产品特性:
» WNT-3a,Mouse活性经过NIH 3T3 细胞鉴定,纯度高
» 生物活性在NIH 3T3 细胞经过TCF报告基因实验鉴定The EC50为 50–150 ng/ml
» WNT-3a,Mouse产品经过SDS-PAGE 和HPLC双层鉴定纯度大于90%
» 只限于研究,非人体使用
WNT-3a,Mouse 产品英文简述:
WNT-3a is a member of the WNT family of signaling proteins that play a key role in embryonic development and the integrity of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the β-catenin pathway. The predicted size of mouse WNT-3a is a monomeric protein containing 333 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 40 kDa by SDS-PAGE analysis under nonreducing conditions. StemRD’s product is expressed from a mouse cell line overexpressing mouse WNT-3a. Purification is performed with a proprietary process that is distinct from the published method.
• Purity: Greater than 90% as determined by SDS-PAGE analysis
• Biological Activity: The activity was determined by using a TCF reporter gene assay in NIH3T3 cells. The EC50 ranges from 50 – 150 ng/ml. Country of Origin USA
©
金山科研平台是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:
https://16ao.com/thread-15465.htm
© WNT-3a,Mouse 100µg 生长分化因子,产品报价联系微信jinshanbio
特别声明:以上内容(如有图片亦包括在内)来源于授权厂家或网络,如有侵权,请联系删除,本平台不提供信息存储服务。
Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.