产品英文名称：WNT-3a, Human

产品中文名称：人重组WNT-3a蛋白

人重组WNT-3a蛋白 产品简介：

StemRD已研发出一种新颖的表达和纯化诸如WNT蛋白等“困难”蛋白的先进方法。我们独特的处理方法能得到纯度和活性均领先于市场方法生产的WNT蛋白。StemRD的WNT蛋白绝不含有现今市场普遍使用的WNT蛋白中含有的某些非特异性成分。

WNT-3a 是WNT 信号蛋白家庭的成员之一，在胚胎成长和成体组织维护方面起关键作用。WNT-3a 是典型的通过β-联蛋白通路发送信号。已有规格的WNT-3a是一个包含328个氨基酸残基的单链蛋白质。由于糖基化，WNT-3a 在非还原条件下用SDS-PAGE处理会明显损失掉38-41 kDa分子量。StemRD公司生产的WNT-3a是用人体细胞系中Wnt-3a cDNA 在无蛋白培养基上过度表达得到。使用特有的纯化方法，区别于其它已发表的纯化方法，提高蛋白纯度。

人重组WNT-3a蛋白 产品特性：

» WNT-3a使用LC/MS 层析，纯度大于98%，结构经过NMR验证

» 生物活性认证：经过生物试验验证，优于其它同类型产品

» WNT-3a 是典型的通过β-联蛋白通路发送信号

» 仅限用于科学研究，非人体使用

WNT-3a, Human 产品英文简述：

We express and purify WNT proteins by using a proprietary process that is distinctive from the published protocol. Our method results in WNT proteins that are purer and more active than market-leading products which have been associated with non-specific artifacts.

WNT-3a is a member of the WNT family of signaling proteins that play key roles in embryonic development and the maintenance of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the β-catenin pathway. The predicted size of human WNT-3a is a monomeric protein containing 328 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 38 – 41 kDa on SDS-PAGE under non-reducing conditions. StemRD’s WNT-3a is produced from a human cell line overexpressing human Wnt-3a cDNA in protein-free medium. Purification is done by a proprietary process that is distinct from the published method.

WNT all compounds are:

1. >98% pure by LC/MS analysis, and structurally verified by NMR.

2. Bioactivity Certified: tested for biological activities, an advent-age over other supplies.