货号：AB5354

品牌：Merck Millipore

规格：50UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Internexin Antibody, α | AB5354 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: alpha-internexin, C-terminal globular "tail" region. By western blot, AB5354 detects a major band at 66 kDa and a minor band at approximately 150 kDa corresponding to alpha internexin monomer and dimer, respectively. A minor band at approximately 50 kDa is occasionally detected and is believed to be a degradation product of alpha internexin. This antibody has been referred to in the literature as the R36 antibody (Evans, 2002). View All» Immunogen: Full length recombinant rat alpha-internexin fused to E. coli Trp E. View All» Species Reactivity: Mammals View All» Application Notes: Immunohistochemistry on formalin or paraformaldehyde fixed tissues. Immunocytochemistry. Western blot: using human or rat brain homogenates. ELISA Optimal working dilutions must be determined by end user. View All» Control: POSITIVE CONTROL CELLS: PC12, Ntera2. View All» Presentation: Serum liquid, containing no preservatives. View All» Storage Conditions: Maintain frozen at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q16352 View All» Entrez Gene Number: NM_032727.2 View All» Gene Symbol:

• INA

• NF-66

• NEF5

• MGC12702

• Alpha-Inx

• TXBP-1

• Neurofilament-66

• Alpha-internexin
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting

  • Immunocytochemistry

  • Immunohistochemistry
    View All» UniProt Summary: FUNCTION: SwissProt: Q16352 # Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.SIZE: 499 amino acids; 55391 Da TISSUE SPECIFICITY: Found predominantly in adult CNS.DEVELOPMENTAL STAGE: Expressed in brain as early as the 16th week of gestation, and increased rapidly and reached a steady state level by the 18th week of gestation.PTM: O-glycosylated (By similarity). & Phosphorylated upon DNA damage, probably by ATM or ATR.SIMILARITY: SwissProt: Q16352 ## Belongs to the intermediate filament family. View All» Brand Family: Chemicon View All» Product Name: Anti-Internexin Antibody, α | AB5354 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Target / Localization: Cytoplasmic, soma, early neurites View All» Format: Serum View All» Host: Rabbit View All»
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