货号：AB5062P

品牌：Merck Millipore

规格：50Ug

目录价：￥5820.00

市场价格：￥4947.00

会员价格：￥4656.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Vesicular GABA Transporter (VGAT) Antibody | AB5062P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Specific for Vesicular GABA Transporter (VGAT). Vesicular GABA Transporter (unc-47) homologue is a 525 amino acid long protein belonging to the family of neurotransmitter transporter. The immunogen peptide shows no significant homology with other known proteins. View All» Molecular Weight: 57 kDa View All» Epitope: C-terminus View All» Immunogen: A 17 amino acid peptide sequence near the carboxy terminal region of rat VGAT (McIntire, S., 1997). View All» Background Information: Vesicular GABA Transporter (unc-47) homologue is a 525 amino acid long protein belonging to the family of neurotransmitter transporter (1). VGAT functions in the uptake of GABA and glycine into synaptic vesicles. Since the protein is bound to synaptic vesicles, VGAT antibodies are excellent markers of presynaptic GABAergic and glycinergic neurons. View All» Species Reactivity:

• Rat

• Mouse

• Human

• Monkey
  View All» Species Reactivity Note: Rat. Antibody cross-reactivity with various species is not known. The immunogen sequence is 100% conserved in mouse, human and monkey. View All» Application Notes: Immunohistochemistry/Immunofluorescence: 2-20 µg/mL of a previous lot was used on paraformaldehyde fixed sections.ELISA: 1:10,000 – 1:100,000 dilution of a previous lot was used on ELISA, using 50-100 ng of control peptide (Cat. No. AG379) per well.Western blot: 1-10 µg/mL (Chemiluminescence technique) The expected molecular weight is approximately 55-60 kDa. Optimal working dilutions must be determined by the end user. View All» Control: Brain tissue, rat retina lysate View All» Quality Assurance: Evaluated by Western Blot on Rat retina lysates.Western Blot Analysis: 1:500 dilution of this antibody detected Vesicular GABA Transporter on 10μg of rat retina lysates. View All» Purification Method: Immunoaffinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing PBS with 0.1% BSA and 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt. View All» UniProt Number: Q9H598 View All» Entrez Gene Number: NM_080552.2 View All» Gene Symbol:
  • SLC32A1

  • VIAAT

  • VGAT

  • bA122O1.1

  • hVIAAT
    View All» Alternate Names: Vesicular Inhibitory Amino Acid Transporter View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunofluorescence

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II. View All» UniProt Summary: FUNCTION: SwissProt: Q9H598 # Involved in the uptake of GABA and glycine into the synaptic vesicles.SIZE: 525 amino acids; 57415 Da SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Multi-pass membrane protein (By similarity).TISSUE SPECIFICITY : Retina. Expressed throughout the horizontal cells or more specifically at the terminals.SIMILARITY: SwissProt: Q9H598 ## Belongs to the amino acid/polyamine transporter 2 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Vesicular GABA Transporter (VGAT) Antibody | AB5062P View All» Concentration: 1 mg/ml View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μg View All» Target / Localization: Presynaptic View All» Format: Affinity Purified View All» Host: Rabbit View All»
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