货号：AB4330

品牌：Merck Millipore

规格：100UL

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-DDX4 (Vasa) Antibody | AB4330 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes DDX4 (Vasa) at the C-terminus. View All» Molecular Weight: ~76 kDa observed View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of mouse DDX4 (Vasa). View All» Background Information: DDX4 (Vasa or MVH) is a member of the DEAD family of proteins and is a probable ATP-dependent RNA helicase. DDX4 (Vasa) proteins are mostly localized in testicular germ cells in the cytoplasm of spermatocytes. DDX4 (Vasa) is a high-copy extragenic suppressor gene. DDX4 (Vasa) is shown to be significantly decreased in spermatozoa of men that are infertile and may have an important role in male fertility. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. View All» Application Notes: Immunohistochemistry Analysis: A 1:100-250 dilution from a previous lot detected DDX4 (Vasa) in normal human testis tissue. View All» Control: Mouse testis tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse testis tissue lysate.Western Blot Analysis: A 1:500 dilution of this antibody detected DDX4 (Vasa) in 10 µg of mouse testis tissue lysate. Western Blot performed without Tween. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q61496 View All» Entrez Gene Number: NP_034159 View All» Gene Symbol:
  • VASA

  • MVH

  • DDX4
    View All» Alternate Names:
    • DEAD (Asp-Glu-Ala-Asp) box polypeptide 4

    • probable ATP-dependent RNA helicase DDX4

    • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4

    • Vasa homolog

    • DEAD box protein 4
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry (Paraffin)
        View All» UniProt Summary: FUNCTION: May play a role in germ cell development.CATALYTIC ACTIVITY: ATP + H2O = ADP + phosphate.SUBUNIT STRUCTURE: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. N-terminus interacts with RANBP9. Interacts with PIWIL2 and MAEL. Ref.3 SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm › perinuclear region. TISSUE SPECIFICTY: Testis.DEVELOPMENTAL STAGE: Expressed in spermatogenic cells from the spermatocyte stage to the round spermatid stage.SEQUENCE SIMILARITIES: Belongs to the DEAD box helicase family. DDX4/VASA subfamily.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain. View All» Product Name: Anti-DDX4 (Vasa) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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