货号：AB3874

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-SENP2 Antibody | AB3874 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes human SENP2. View All» Immunogen: Synthetic peptide corresponding to amino acid residues 16-32 of human SENP2 (CDRSVPPARALLKRRRS). View All» Species Reactivity: Human View All» Application Notes: Western blot: 1:500 (approximately 69 kDa) ELISA: 1:1,000 Optimal working dilutions must be determined by the end user. View All» Control: POSITIVE CONTROL: Jurkat or NIH3T3 whole cell lysate. View All» Presentation: Immunoglobulin was purified by protein G affinitychromatography and is presented as a liquid in PBS with 0.09% sodium azide. View All» Storage Conditions: Maintain at -20ºC in undiluted aliquots for up to one year from date of receipt. View All» UniProt Number: Q9HC62 View All» Entrez Gene Number: NM_021627.2 View All» Gene Symbol:

• SENP2

• AXAM2

• SMT3IP2

• Axam2

• Smt3ip2

• KIAA1331

• DKFZp762A2316

• EC 3.4.22.-
  View All» Alternate Names: Sentrin/SUMO-specific Protease 2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting
    View All» Entrez Gene Summary: SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: Q9HC62 # Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway (By similarity).SIZE: 589 amino acids; 67855 Da SUBUNIT: Binds to SUMO2 and SUMO3 (By similarity). Interacts with the C-terminal domain of NUP153 via its N-terminus.SUBCELLULAR LOCATION: Nucleus, nuclear pore complex; Nucleoplasmic side. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.DOMAIN:SwissProt: Q9HC62 The N-terminus is necessary and sufficient for nuclear envelope targeting.PTM: Polyubiquitinated; which leads to proteasomal degradation.SIMILARITY: Belongs to the peptidase C48 family. View All» Brand Family: Chemicon View All» Product Name: Anti-SENP2 Antibody | AB3874 View All» Concentration: 0.25 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Rabbit View All»
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