货号：AB3794

品牌：Merck Millipore

规格：

目录价：￥3077.00

市场价格：￥2615.45

会员价格：￥2461.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Paxillin Antibody | AB3794 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Paxillin View All» Molecular Weight: 68 kDa View All» Immunogen: Recombinant human paxillin. View All» Species Reactivity:

• Human

• Mouse

• Rat

• Rabbit
  View All» Application Notes: Western blot: 1:1,000 on mouse brain lysates. Immunohistochemistry: 1:10. Immunoprecipitation: 5 μL/mL lysate Optimal working dilutions must be determined by the end user. View All» Presentation: Purified immunoglobulin. Liquid in PBS with 50% Glycerol and 0.01% sodium azide, pH 7.3. View All» Storage Conditions: Maintain at -20°C in undiluted for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P49023 View All» Entrez Gene Number: NM_002859.1 View All» Gene Symbol:
  • PXN

  • Paxillin.

  • paxillin

  • FLJ16691
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

    • Immunohistochemistry
      View All» UniProt Summary: FUNCTION: SwissProt: P49023 # Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).SIZE: 591 amino acids; 64533 Da SUBUNIT: Binds in vitro to vinculin as well as to the SH3 domain of c-SRC and, when tyrosine phosphorylated, to the SH2 domain of V-CRK. Isoform beta binds to focal adhesion kinase but weakly to vinculin. Isoform gamma binds to vinculin but only weakly to focal adhesion kinase. Interacts with GIT1, NUDT16L1/SDOS, PARVA and TGFB1I1. Component of cytoplasmic complexes, which also contain GIT1, ARHGEF6 and PAK1 (By similarity). Binds DDEF2. Interacts with unphosphorylated ITGA4. Interacts with RNF5.PTM: Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.SIMILARITY: SwissProt: P49023 ## Belongs to the paxillin family. & Contains 4 LIM zinc-binding domains. View All» Brand Family: Chemicon View All» Product Name: Anti-Paxillin Antibody | AB3794 View All» Concentration: 100 μg/150 μL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Purified View All» Host: Rabbit View All»
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