货号：AB3434

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Surfactant Protein D Antibody | AB3434 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts strongly with mouse SP-D. View All» Molecular Weight: 43 kDa View All» Immunogen: Purified mouse SP-D from double null mutant mice for SP-A {Stahlman MT et al. (2002) J. Histochem Cytochem 50(5):651-660.} in incomplete Freund's adjuvant. View All» Background Information: Immunoreactive surfactant protein-D (SP-D) is a widely distributed member of the collectin family of polypeptides found in fetal, newborn and adult tissue. SP-D binds to bacterial lipopolysaccharide as well as to carbohydrate-rich surfaces of many bacteria, viruses, fungi and allergens. The protein is secreted onto luminal surfaces by epithelial cells lining ducts of many organs, where it likely plays roles in innate host defense, antioxidation and inflammation regulation mechanisms. View All» Species Reactivity:

• Human

• Mouse
  View All» Application Notes: Immunoblot: 1:1,000-1:5,000; detects a 43kDa band in mouse lavage fluid. ELISA: 1:1,000-1:5,000 Immunohistochemistry: On paraffin sections. Optimal dilutions must be determined by the end user. View All» Control: Lung tissue, lung lavage. View All» Quality Assurance: Antibody is post-absorbed with lung homogenate from SP-D-1 null mice. {Stahlman, MT et al 2002} View All» Purification Method: Unpurified View All» Presentation: Rabbit Serum. Liquid. Contains no preservative. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P35247 View All» Entrez Gene Number: NM_003019.4 View All» Gene Symbol:
  • SFTPD

  • PSP-D

  • SP-D

  • SFTP4

  • PSPD

  • COLEC7
    View All» Alternate Names: SP-D View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunohistochemistry (Paraffin)

    • Western Blotting
      View All» UniProt Summary: FUNCTION: SwissProt: P35247 # Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.SIZE: 375 amino acids; 37698 Da SUBUNIT: Oligomeric complex of 4 set of homotrimers.SUBCELLULAR LOCATION: Secreted, extracellular space.PTM: The N-terminus is blocked. & Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates (By similarity).SIMILARITY: SwissProt: P35247 ## Contains 1 C-type lectin domain. & Contains 1 collagen-like domain. MISCELLANEOUS: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C)." View All» Brand Family: Chemicon View All» Product Name: Anti-Surfactant Protein D Antibody | AB3434 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Serum View All» Host: Rabbit View All»
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