货号：AB3276-50UL

品牌：Merck Millipore

规格：50UL

目录价：￥4884.00

市场价格：￥4151.40

会员价格：￥3907.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Aquaporin 3 Antibody | AB3276-50UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Aquaporin 3. View All» Molecular Weight: 31kDa and 40kDa View All» Immunogen: Highly purified peptide corresponding to residues 275-292 of rat Aquaporin 3 (Accession Number P47862) coupled to KLH. View All» Species Reactivity:

• Mouse

• Rat
  View All» Application Notes: Western blotting: 1:200 on rat kidney membranes. Identifies a 31kDa and 40kDa band. The large band may represent the glycosylated form of the protein. Immunohistochemistry on mouse kidney sections. Dilutions should be made using a carrier protein such as BSA (1-3%). Optimal working dilutions must be determined by the end user. View All» Control: Included free of charge with the antibody is 20 μg of control antigen (lyophilized powder). Reconstitute with 100 μL of deionized water. For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Affinity Purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA and 0.025% sodium azide. Reconstitute with 50 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min). View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 6 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q92482 View All» Entrez Gene Number: NM_004925.3 View All» Gene Symbol:
  • AQP3

  • AQP-3

  • Aquaporin-3

  • GIL
    View All» Alternate Names: AQP3; GLIP View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: Aquaporin 3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. View All» UniProt Summary: FUNCTION: SwissProt: Q92482 # Forms a water-specific channel that provide kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. May function as a water and urea exit mechanism in antidiuresis in collecting duct cells. Also slightly permeable to urea and glycerol. May play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity).SIZE: 292 amino acids; 31544 Da SUBCELLULAR LOCATION: Basolateral cell membrane; Multi-pass membrane protein. Note=In collecting ducts of kidney.TISSUE SPECIFICITY: Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.DOMAIN:SwissProt: Q92482 Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family. View All» Brand Family: Chemicon View All» Product Name: Anti-Aquaporin 3 Antibody | AB3276-50UL View All» Concentration: 0.3 mg/mL (after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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