货号：AB3241-25UL

品牌：Merck Millipore

规格：25UL

目录价：￥1295.00

市场价格：￥1100.75

会员价格：￥1036.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cdc2 Antibody, phospho-specific (Tyr15) | AB3241-25UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: CDC2, phosphoTyr15. By Western blot the antibody recognizes the ~35 kDa phospho CDC2 protein. The labeling of the CDC2 band in Western blots of rat brain is blocked by the phosphopeptide but not by the dephosphopeptide. View All» Epitope: phospho-specific (Tyr15) View All» Immunogen: Synthetic peptide corresponding to amino acids surrounding the phosphoTry15 of human, rat, mouse and Xenopus CDC2. View All» Modifications: Phosphorylation View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:1,000 Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin in 10 mM Hepes, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. View All» Storage Conditions: Maintain at -20°C in undiluted for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer. View All» UniProt Number: P06493 View All» Entrez Gene Number:

• NM_001786.2

• NM_033379.2
  View All» Gene Symbol:
  • CDC2

  • CDK1

  • DKFZp686L20222

  • MGC111195

  • CDC28A

  • EC 2.7.11.22

  • EC 2.7.11.23
    View All» Alternate Names: Cell Division Cycle 2; p34 Protein Kinase; Cyclin-dependent Kinase 1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. View All» UniProt Summary: FUNCTION: SwissProt: P06493 # Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.SIZE: 297 amino acids; 34095 Da SUBUNIT: Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with DLG7. Isoform 2 is unable to complex with cyclin B1 and also fails to bind to the CDK inhibitor p21. Interacts with catalytically active CCNB1 and RALBP1 during mitosis to form an endocytotic complex during interphase.SUBCELLULAR LOCATION: Nucleus (By similarity).SIMILARITY: SwissProt: P06493 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. & Contains 1 protein kinase domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Cdc2 Antibody, phospho-specific (Tyr15) | AB3241-25UL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 25 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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