Merck Millipore代理AB3094 Anti-Orexin-2 Receptor Antibody;抗促食欲素-2受体抗体store at -20℃

2025-06-28

货号:AB3094

品牌:Merck Millipore

规格:50Ug

目录价:¥6588.00

市场价格:¥5599.80

会员价格:¥5270.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Orexin-2 Receptor Antibody | AB3094 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Rat/Human Orexin-2. Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (Sakurai et al. 1998). Orexin-A and Orexin-B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. Prepro-orexin is an 130 aa peptide with a putative 33 aa secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis (Sakurai et al. 1998). These neuropeptides bind and activate two closely related Orexin receptors--G protein coupled receptors (GPCRs) OX1R and OX2R. View All» Immunogen: A 19 aa peptide near the C-terminus (cytoplasmic domain) of rat OX2R. The immunogen peptide (Catalog Number AG794) is available to perform preabsorbtion controls. View All» Species Reactivity:

  • Human

  • Mouse

  • Rat

    View All» Application Notes: Western blot: 1-10 μg/mL using Chemiluminescence technique ELISA: 1:10,000 - 100,000 against the control peptide (Catalog Number AG794). Optimal working dilutions must be determined by end user. View All» Presentation: Affinity Purified 1mg/mL solution in PBS, pH 7.4 and 0.1% BSA View All» Storage Conditions: Maintain frozen at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: O43614 View All» Entrez Gene Number: NP_001517 View All» Gene Symbol:
    • HCRTR2

    • OTTHUMP00000039969

    • Ox2r

    • OX2R

      View All» Alternate Names: OX2R; Hypocretin Receptor 2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • ELISA

      • Immunohistochemistry

      • Western Blotting

        View All» Entrez Gene Summary: HCRTR2 is a G-protein coupled receptor expressed exclusively in the brain. It has 64% identity with HCRTR1. HCRTR2 binds both orexin A and orexin B neuropeptides. HCRTR2 is involved in the central feedback mechanism that regulates feeding behaviour. View All» UniProt Summary: FUNCTION: SwissProt: O43614 # Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.SIZE: 444 amino acids; 50680 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: O43614 ## Belongs to the G-protein coupled receptor 1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Orexin-2 Receptor Antibody | AB3094 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»

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