货号：AB2970

品牌：Merck Millipore

规格：

目录价：￥4118.00

市场价格：￥3500.30

会员价格：￥3294.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MAP1LC3B2 Antibody | AB2970 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes MAP1LC3B2 at the N-terminus. View All» Molecular Weight: ~16 kDa observed View All» Epitope: N-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to human MAP1LC3B2 at the N-terminus. View All» Background Information: Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved in development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The human MAP1LC3 protein is homologous with the rat Map1LC3 and with yeast APG8 proteins. These proteins are likely to be involved in the formation of autophagosomal vacuoles (autophagosomes). View All» Species Reactivity:

• Human

• Mouse

• Rat

• Pig

• Bovine

• Rhesus Macaque
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. Predicted to react with bovine, porcine, and rhesus macaque based on 100% sequence homology. View All» Application Notes: Western Blotting (SNAP i.d.® Protein Detection System) Analysis: 5 µg/mL from a previous lot detected MAP1LC3B2 on 10 µg of HeLa cell lysate.Immunohistochemistry (paraffin) Analysis: A 1:500 dilution from a previous lot detected MAP1LC3B2 in colorectal carcinoma tissue. View All» Control: HeLa cell lysate View All» Quality Assurance: Evaluated by Western Blot in HeLa cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected MAP1LC3B2 on 10 µg of HeLa cell lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt View All» UniProt Number: A6NCE7 View All» Entrez Gene Number: A6NCE7 View All» Gene Symbol: ATG8G View All» Alternate Names:
  • microtubule-associated protein 1 light chain 3 beta 2

  • Microtubule-associated proteins 1A/1B light chain 3B-like protein

  • microtubule-associated protein 1 light chain 3 beta-like

  • microtubule-associated proteins 1A/1B light chain 3 beta 2

  • Microtubule-associated proteins 1A/1B light chain 3B-like
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry (Paraffin)
      View All» UniProt Summary: FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes) By similarity.SUBUNIT STRUCTURE: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins By similarity.SUBCELLULAR LOCATION: Cytoplasm By similarity. Endomembrane system; Lipid-anchor By similarity. Cytoplasmic vesicle › autophagosome membrane; Lipid-anchor By similarity. Note: LC3-II binds to the autophagic membranes By similarity.PTM: The precursor molecule is cleaved by APG4B/ATG4B to form LC3-I By similarity. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form LC3-II By similarity.SEQUENCE SIMILARITIES: Belongs to the MAP1 LC3 family. View All» Product Name: Anti-MAP1LC3B2 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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