货号：AB2218

品牌：Merck Millipore

规格：100Ug

目录价：￥6588.00

市场价格：￥5599.80

会员价格：￥5270.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Aquaporin 4 Antibody | AB2218 View All» Replaces: Cat. # AB3068 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Aquaporin 4. View All» Molecular Weight: ~34 kDa View All» Epitope: C-Terminus View All» Immunogen: Synthetic Linear Peptide View All» Background Information: The water-specific channel Aquaporin 4 is located in various tissues including the gastro intestinal tract, kidney and brain. It is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. The localization of AQ4 to astrocyte endfeet makes it an excellent marker for astrocyte distal processes. View All» Species Reactivity: Rat View All» Species Reactivity Note: The antibody has not yet been tested for cross-reactivity to other species. The immunogen shows 94% similarity to mouse, 88% to bovine, 86% to rabbit and 82% to human AQP4 (hAQP4). View All» Application Notes: Western Blotting: 0.5-1 μg/mL using Chemiluminescence technique.Optimal working dilutions must be determined by end user. View All» Control: Tested on adult rat brain lysate View All» Purification Method: Immunoaffinity purified View All» Presentation: Purified in PBS with 0.05% NaN₃ View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. View All» UniProt Number: P55087 View All» Entrez Gene Number:

• NM_001650.4

• NM_004028.3
  View All» Gene Symbol:
  • AQP4

  • MIWC

  • WCH4

  • AQP-4

  • aquaporin-4

  • HMIWC2

  • Aquaporin-4

  • MGC22454
    View All» Alternate Names: AQP4; WCH4; MIWC View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P55087 # Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.SIZE: 323 amino acids; 34830 Da SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Brain - muscle > heart, kidney, lung, and trachea.DOMAIN: SwissProt: P55087 Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family. View All» Product Name: Anti-Aquaporin 4 Antibody | AB2218 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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