货号：AB2205

品牌：Merck Millipore

规格：EA

目录价：￥3828.00

市场价格：￥3253.80

会员价格：￥3062.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PAT2 Antibody | AB2205 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes PAT2. View All» Molecular Weight: Band observed at 55 kDa. View All» Epitope: Extracellular Domain View All» Immunogen: KLH-conjugated linear peptide corresponding to rat PAT2. View All» Background Information: PAT2, also known as Tramdorin-1, is a protein that belongs to the amino acid/polyamine transporter 2 family. PAT2 is believed to be involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids such as glycine, alanine and proline. PAT2 is found expressed in lung, spleen, and to a lower extent in brain, heart, kidney and skeletal muscle. PAT2 can be inhibited by sarcosine, pipecolic acid, D-pipecolic acid or isonipecotic acid. View All» Species Reactivity:

• Rat

• Mouse
  View All» Species Reactivity Note: Proven to react with rat and mouse. Human and Orangutan (86%). View All» Application Notes: Immunohistochemistry Analysis: 1:100 dilution from a previous lot detected PAT2 in mouse hippocampus and brain tissue. View All» Control: Rat brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in rat brain tissue lysate.Western Blot Analysis: 1 µg/ml of this antibody detected PAT2 on 10 µg of rat brain tissue lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8K415 View All» Entrez Gene Number: NP_647555.1 View All» Gene Symbol:
  • PAT2

  • TRAMD1

  • Tramdorin-1

  • tramdorin

  • SLC36A2
    View All» Alternate Names:
    • Proton/amino acid transporter 2

    • Solute carrier family 36 member 2

    • solute carrier family 36 (proton/amino acid symporter), member 2

    • solute carrier family 36, member 2, Solute carrier family 36 (proton/amino acid symporter) member 2, FLJ16051, MGC119658, MGC119660, PAT2, TRAMD1, Tramdorin

    • A530067G19Rik, Proton coupled amino acid transporter 2, Tramdorin 1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Entrez Gene Summary: Regulates pH-dependent, Na(+)-independent uptake of glycine, proline, and alpha(methyl)aminoisobutyric acid (MeAIB) [RGD] View All» UniProt Summary: FUNCTION: Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine. Inhibited by L-pipecolic acid, D-pipecolic acid and isonipecotic acid. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cytoplasm By similarity. TISSUE SPECIFICTY: Expressed in lung and spleen, and to a lower extent in brain, heart, kidney and skeletal muscle.SEQUENCE SIMILARITIES: Belongs to the amino acid/polyamine transporter 2 family.BIOPHYSICAL PROPERTIES: Kinetic parameters:KM=0.172 mM for proline View All» Product Name: Anti-PAT2 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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