货号：AB2202

品牌：Merck Millipore

规格：100UL

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PER2 Antibody | AB2202 View All» Promotional Text: Special Offer on Antibodies! Click Here! View All» Trade Name: Chemicon (Millipore) View All» Specificity: Cat. # AB2202 will recognize the N-terminus of PER2. View All» Molecular Weight: Approx. 136 kDa. Band may be observed at a much higher 200 kDa by the liver product depending on level of phophorylation and gel system used. View All» Immunogen: Synthetic peptide. View All» Background Information: PER2 is a component of the circadian clock mechanism which is essential for generating circadian rhythms. It is a negative element in the circadian transcriptional loop by Influencing clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. PER2 negatively regulates CLOCK NPAS2-BMAL1 BMAL2-induced transactivation. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. View All» Species Reactivity:

• Mouse

• Rat
  View All» Species Reactivity Note: Mouse and Rat. Reactivity with other species has not been determined. View All» Application Notes: Western Blot Analysis:C2C12 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PER2 (1:500 dilution of this lot). Proteins were visualized using a Donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. View All» Control: C2C12 tissue lysate. View All» Quality Assurance: Routinely evaluated by western blot on C2C12 lysate. View All» Presentation: Serum with 0.05% NaN3 View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt. View All» UniProt Number: O54943 View All» Entrez Gene Number: NP_035196 View All» Gene Symbol:
  • FASPS

  • KIAA0347

  • hPER2
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-PER2 Antibody | AB2202 View All» Concentration: See data sheet View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Host: Rabbit View All»
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