货号：AB19014

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Vitronectin Antibody | AB19014 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reactive with Vitronectin as confirmed by Immunohistochemistry View All» Immunogen: Purified human plasma Vitronectin. Human vitronectin shows greater than 68% amino acid identity with Vitronectin from rabbit, mouse, and pig View All» Species Reactivity: Human View All» Application Notes: Immunohistochemistry 1:50 - 1:500 ELISA: 1:1,000 to 1:10,000 Optimal working dilutions must be determined by end user. View All» Presentation: Chromatographically purified Immunoglobulin. Liquid in 0.02 M phosphate buffer, 0.25 M NaCl, pH 7.6, containing 0.1% sodium azide as a preservative View All» Storage Conditions: Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. View All» UniProt Number: P04004 View All» Entrez Gene Number: NM_000638.3 View All» Gene Symbol:

• VTN

• S-protein

• epibolin

• VNT

• VN

• V75
  View All» Alternate Names: Serum spreading factor; S-protein View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Immunohistochemistry
    View All» Entrez Gene Summary: The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. View All» UniProt Summary: FUNCTION: SwissProt: P04004 # Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.SIZE: 478 amino acids; 54306 Da SUBUNIT: Exists in two forms: a single chain 75 kDa form (V75) and a clipped form composed of two chains (65 kDa and 10 kDa) (V65+V10) which are held together by a disulfide bond. Interacts with SERPINE1/PAI1 and insulin.SUBCELLULAR LOCATION: Secreted, extracellular space.TISSUE SPECIFICITY: Plasma.DOMAIN: SwissProt: P04004 The SMB domain mediates interaction with SERPINE1/PAI1. The heparin-binding domain mediates interaction with insulin.PTM: Sulfated on 2 tyrosine residues. & N- and O-glycosylated (By similarity). & Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading. & It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.SIMILARITY: Contains 4 hemopexin-like domains. & Contains 1 SMB (somatomedin-B) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Vitronectin Antibody | AB19014 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Rabbit View All»
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