金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:ELISA Development Kit for intracellular proteins Assay Length:4 hours 40 mins (after plate preparation) Sample Type & Volume Required:Cell lysates (100 µL) Sufficient Materials:Kits available for two, five, or fifteen 96-well plates* Range:15.6 - 1,000 pg/mL Specificity:Please see the product datasheet Molecule Information: Paxillin Aliases: PXN Entrez Gene IDs: 5829 (Human); 19303 (Mouse); 360820 (Rat) Background: Paxillin Paxillin is a 65 kDa cytoskeletal adaptor protein and member of the Paxillin family. Paxillin is found at the interface between actin filaments and the plasma membrane, and it localizes to focal adhesions, where it provides a platform for the integration and coordination of adhesion- and growth factor-related signals. Paxillin phosphorylation at tyrosines 31 and 118 is required for integrin-mediated cytoskeletal reorganization, and may play a role in the disassembly of focal adhesions and stress fibers during cellular transformation.