货号：AB1597P

品牌：Merck Millipore

规格：1EA

目录价：￥5613.84

市场价格：￥4771.76

会员价格：￥4491.07

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Vesicular Monoamine Transporter 1 Antibody | AB1597P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Vesicular Monoamine Transporter 1 (VMAT1). An antibody made to the C-terminal VMAT1 peptide detected a major band at ~55 kDa in postnuclear supernatants of CHO transfected with VMAT1 and not in wild type cells (Liu et al. 1994). Some additional bands, both higher and lower molecular weight, were also detected and remain unaffected by the inclusion of protease inhibitors. VMAT1 has been localized in adrenal chromaffin cells, endocrine and paracrine cells associated with the intestine, stomach and sympathetic nervous system (Liu et al. 1994; Weihe et al. 1994). VMAT1 has also been found in endosomes of transfected CHO cells and in LDCVs of rat PC12 cells (Liu et al. 1994). This antibody is not expected to cross-react with human VMAT1 (Erickson et al. 1996). View All» Immunogen: A 12 amino acid C-terminal peptide sequence from rat VMAT1 (Liu et al. 1992). This peptide is predicted to be cytoplasmic. View All» Species Reactivity:

• Mouse

• Rat
  View All» Application Notes: Western blot: 1-10 μg/mL (Chemiluminescence technique) Immunohistochemistry: 1-20 μg/mL on paraformaldehyde fixed sections. ELISA: 0.5-1.0 μg/mL (1 μg/mL VMAT1 peptide (Catalog Number AG250)/well) Optimal working dilutions must be determined by end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P54219 View All» Entrez Gene Number: NM_003053.1 View All» Gene Symbol:
  • SLC18A1

  • VAT1

  • CGAT

  • VMAT1
    View All» Alternate Names: VMAT1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P54219 # Involved in the vesicular transport of biogenic amines.SIZE: 525 amino acids; 56257 Da SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P54219 ## Belongs to the major facilitator superfamily. Vesicular transporter family. View All» Brand Family: Chemicon View All» Product Name: Anti-Vesicular Monoamine Transporter 1 Antibody | AB1597P View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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