货号：AB1569

品牌：Merck Millipore

规格：100UL

目录价：￥5666.00

市场价格：￥4816.10

会员价格：￥4532.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Dopa Decarboxylase Antibody | AB1569 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: DOPA Decarboxylase (DDC). Reacts with a single band of ~55 kDa by Western blot. View All» Immunogen: Recombinant bovine DDC expressed in E. coli and purified from inclusion bodies. View All» Species Reactivity:

• Bovine

• Canine

• Guinea Pig

• Human

• Rat

• Sheep
  View All» Application Notes: Immunoblotting: 1:500-1:1,000 Immunohistochemistry using formaldehyde-fixed brain sections. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. View All» Storage Conditions: Maintain at -20 to -80°C in undiluted aliquots for up to six months after date of receipt. Store in a NON-self-defrosting freezer. Avoid repeated freeze-thaw cycles. View All» UniProt Number: P20711 View All» Entrez Gene Number:
  • NM_000790.3

  • NM_001082971.1
    View All» Gene Symbol:
    • DDC

    • AADC

    • EC 4.1.1.28
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunohistochemistry

      • Western Blotting
        View All» UniProt Summary: FUNCTION: SwissProt: P20711 # Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.COFACTOR: Pyridoxal phosphate.SIZE: 480 amino acids; 53894 Da SUBUNIT: Homodimer.DISEASE: SwissProt: P20711 # Defects in DDC are the cause of aromatic-L-amino-acid decarboxylase deficiency (AADC deficiency) [MIM:608643]. AADC deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive.SIMILARITY: SwissProt: P20711 ## Belongs to the group II decarboxylase family. View All» Brand Family: Chemicon View All» Product Name: Anti-Dopa Decarboxylase Antibody | AB1569 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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