货号：AB15520

品牌：Merck Millipore

规格：1EA

目录价：￥5613.84

市场价格：￥4771.76

会员价格：￥4491.07

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neuronal pentraxin 2 Antibody | AB15520 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Immunogen: Synthetic peptide near the N-terminus of mouse NPX2 View All» Background Information: Neuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPX2 (Neuronal Pentraxin 2), 429aa in mouse, 432 in rat and 431 in human (chr 7q21), mainly expressed in brain, pancrease, liver and testis. It is likely to play role in the modification of cellular properties that underlie long-term plasticity. NPX1, NPX2 has potential N-linked glycosylation sites. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Other species have not yet been tested. The immunogen sequence is 100% conserved in rat, and 94% in human NPX2 and 82% in guinea pig apexin precursor P50. View All» Application Notes: Western blot: 1-10 µg/mL using ECL. Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 µg/mL ELISA: 1:10,000-1:100,000 using 50-100 ng of control peptide/well. Optimal working dilutions must be determined by end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Liquid in 100 mM Tris, pH 7.5, with 0.2% BSA and 0.05% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P47972 View All» Entrez Gene Number: NM_002523.1 View All» Gene Symbol:

• NPTX2

• NP-II

• NP2

• NARP
  View All» Alternate Names: NPX2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting
    View All» UniProt Summary: FUNCTION: SwissProt: P47972 # Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity).COFACTOR: Binds 2 calcium ions per subunit (By similarity).SIZE: 431 amino acids; 47042 Da SUBCELLULAR LOCATION: Secreted (By similarity).TISSUE SPECIFICITY: Brain, pancreas, liver, heart and skeletal muscle. Highest levels are seen in the testis.SIMILARITY: SwissProt: P47972 ## Contains 1 pentaxin domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Neuronal pentraxin 2 Antibody | AB15520 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Purified View All» Host: Rabbit View All»
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