货号：AB1550

品牌：Merck Millipore

规格：

目录价：￥3433.00

市场价格：￥2918.05

会员价格：￥2746.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Calretinin Antibody | AB1550 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Calretinin. View All» Molecular Weight: 31.4 kDa View All» Immunogen: Rat calretinin. View All» Species Reactivity:

• Guinea Pig

• Human

• Mouse

• Rat
  View All» Application Notes: Western blot at 1:10,000. Immunohistochemistry: IFA at 1:2,500, PAP at 1:2,500 (48 hours at +4 C). Optimal working dilutions must be determined by the end user. View All» Control: Rat brain cortex, Mesothelioma tissue View All» Purification Method: Unpurified View All» Presentation: UnPurified goat Serum containing no preservatives. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P22676 View All» Entrez Gene Number:
  • NM_001740.3

  • NM_007087.2

  • NM_007088.2
    View All» Gene Symbol:
    • CALB2

    • Calretinin

    • CAB29

    • CR

    • CAL2
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunohistochemistry

      • Western Blotting
        View All» Entrez Gene Summary: Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin 2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin 1. Calbindin 2 contains five presumably active and one presumably inactive calcium-binding domains. Comparison with the partial sequences available for chick and guinea pig calbindin 2 reveals that the protein is highly conserved in evolution. The calbindin 2 message was detected in the brain, while absent from heart muscle, kidney, liver, lung, spleen, stomach and thyroid gland. There are two additional forms of alternatively spliced calbindin 2 mRNAs encoding C-terminally truncated proteins. Exon 7 can splice to exon 9, resulting in a frame shift and a translational stop at the second codon of exon 9, and encoding calretinin-20k. Exon 7 can also splice to exon 10, resulting in a frame shift and a translational stop at codon 15 of exon 10, and encoding calretinin-22k. The truncated proteins are able to bind calcium. View All» UniProt Summary: FUNCTION: SwissProt: P22676 # Calretinin is a calcium-binding protein which is abundant in auditory neurons.SIZE: 271 amino acids; 31540 Da TISSUE SPECIFICITY: Brain.SIMILARITY: SwissProt: P22676 ## Belongs to the calbindin family. & Contains 6 EF-hand domains. View All» Brand Family: Chemicon View All» Product Name: Anti-Calretinin Antibody | AB1550 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Serum View All» Host: Goat View All»
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