货号：AB15467P

品牌：Merck Millipore

规格：500MIG

目录价：￥6588.00

市场价格：￥5599.80

会员价格：￥5270.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ARG3.1 Antibody | AB15467P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: ARG3.1 [Growth factor ARC, Activity regulated cytoskeleton] View All» Immunogen: Synthetic peptide corresponding to a region within the C-terminus of human ARG3.1 protein. View All» Background Information: Arc/Arg3.1 is an immediate-early gene whose mRNA is rapidly transcribed and targeted to dendrites of neurons as they engage in information processing and storage. Arc/Arg3.1 is known to be required for durable forms of synaptic plasticity and learning. Arc/Arg3.1 has been shown to be expressed in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus. View All» Species Reactivity: Rat View All» Application Notes: Immunohistochemistry: 1:200-1:1,000 Optimal working dilutions must be determined by end user. View All» Presentation: Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative. View All» Storage Conditions: Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability. View All» UniProt Number: Q7LC44 View All» Entrez Gene Number: NM_015193.3 View All» Gene Symbol:

• ARC

• KIAA0278

• Arg3.1

• NOP

• NOL3

• ARC/ARG3.1

• MYC
  View All» Alternate Names: Growth factor ARC, Activity regulated cytoskeleton View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry View All» UniProt Summary: FUNCTION: SwissProt: Q7LC44 # Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity).SIZE: 396 amino acids; 45316 Da SUBUNIT: Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2 (By similarity).SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton (By similarity). Endosome (By similarity). Acrosome (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Cell projection, dendrite (By similarity). Cell projection, dendritic spine (By similarity). Cell junction, synapse (By similarity). Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail (By similarity).SIMILARITY: SwissProt: Q7LC44 ## Belongs to the ARC/ARG3.1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-ARG3.1 Antibody | AB15467P View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 500 µg View All» Target / Localization: Presynaptic, plasticity related View All» Format: Purified View All» Host: Rabbit View All»
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