货号：AB15446

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Rig1/Robo3 Antibody | AB15446 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Rig1/Robo3. By Western blot the antibody recognizes a band at ~200 kDa on mouse brain and spinal cord lysate. An additional band at ~15 kDa may be seen depending on sample and antibody concentration used. View All» Immunogen: Synthetic peptide from mouse Rig1/Robo3. View All» Species Reactivity: Mouse View All» Application Notes: Western blot: 1-2 μg/mL on mouse brain lysate. Optimal working dilutions must be determined by end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Liquid in PBS with 0.1% sodium azide. View All» Storage Conditions: 6 months at 4°C from date of shipment. View All» UniProt Number: Q96MS0 View All» Entrez Gene Number: NM_022370.2 View All» Gene Symbol:

• ROBO3

• RBIG1

• HGPS

• FLJ21044

• HGPPS

• RIG1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: Q96MS0 # Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1 (By similarity). Required for hindbrain axon midline crossing.SIZE: 1386 amino acids; 148209 Da SUBUNIT: Probably interacts with SLIT2 (By similarity).SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).DISEASE:SwissProt: Q96MS0 # Defects in ROBO3 are a cause of familial horizontal gaze palsy with progressive scoliosis (HGPPS) [MIM:607313]. Patients show a medulla where motor and sensory projections appear uncrossed.SIMILARITY: SwissProt: Q96MS0 ## Belongs to the immunoglobulin superfamily. ROBO family. & Contains 3 fibronectin type-III domains. & Contains 5 Ig-like C2-type (immunoglobulin-like) domains. View All» Brand Family: Chemicon View All» Product Name: Anti-Rig1/Robo3 Antibody | AB15446 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Rabbit View All»
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