货号：AB15417

品牌：Merck Millipore

规格：50UL

目录价：￥6526.00

市场价格：￥5547.10

会员价格：￥5220.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Beclin 1 Antibody | AB15417 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Beclin 1 [Coiled-coil myosin-like BCL2-interacting protein, BECN1]. View All» Immunogen: Synthetic peptide corresponding to the C-terminus of human Beclin 1 protein. View All» Background Information: Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. Beclin 1 is a BCL-2 interacting protein and this protein was shown to play a role in the promotion of autophagy. View All» Species Reactivity: Human View All» Application Notes: Western blot: 1:100-1:2,000 Immunocytochemistry: 1:100-1:2,000 Immunohistochemistry: 1:100-1:2,000 Optimal working dilutions must be determined by end user. View All» Purification Method: Serum View All» Presentation: Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative. View All» Storage Conditions: Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability. View All» UniProt Number: Q14457 View All» Entrez Gene Number: NM_003766.2 View All» Gene Symbol:

• BECN1

• GT197

• Beclin-1

• beclin1

• ATG6

• VPS30
  View All» Alternate Names: Coiled-coil myosin-like BCL2-interacting protein, BECN1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry

  • Immunohistochemistry
    View All» UniProt Summary: FUNCTION: SwissProt: Q14457 # May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy.SIZE: 450 amino acids; 51896 Da SUBUNIT: Interacts with GOPC and GRID2 (By similarity). Interacts with BCL2 and BCL2L1.SUBCELLULAR LOCATION: Cytoplasm (Potential). Golgi apparatus membrane; Peripheral membrane protein (By similarity). Note=Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity).TISSUE SPECIFICITY: Ubiquitous.SIMILARITY: SwissProt: Q14457 ## Belongs to the beclin family. View All» Brand Family: Chemicon View All» Product Name: Anti-Beclin 1 Antibody | AB15417 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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