货号：AB15404P

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-APG5 Antibody | AB15404P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: APG5 [Autophagy-related protein 5, APG5-like, ATG5, Apoptosis-specific protein]. View All» Immunogen: Synthetic peptide corresponding to a region within the C-terminus of human APG5 protein. View All» Background Information: Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. APG5 conjugates to APG12 and this conjugate is required for elongation of the isolation membrane to form a complete spherical autophagosome. The APG5 protein may play an important role in the apoptotic process, possibly within the modified cytoskeleton. View All» Species Reactivity: Human View All» Application Notes: Western blot: 1-5 µg/mL Immunocytochemistry: 1-5 µg/mL Immunohistochemistry: 1-5 µg/mL Optimal working dilutions must be determined by end user. View All» Presentation: Lyophilized. Reconstitute with 500 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative. View All» Storage Conditions: Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability. View All» UniProt Number: Q9H1Y0 View All» Entrez Gene Number: NM_004849.2 View All» Gene Symbol:

• ATG5

• ASP

• APG5-like

• APG5

• OTTHUMP00000040507

• APG5L

• hAPG5
  View All» Alternate Names: Autophagy-related protein 5, APG5-like, ATG5, Apoptosis-specific protein View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry

  • Immunohistochemistry
    View All» UniProt Summary: FUNCTION: SwissProt: Q9H1Y0 # May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.SIZE: 275 amino acids; 32447 Da SUBCELLULAR LOCATION: Cytoplasm. Note=Colocalizes with nonmuscle actin.TISSUE SPECIFICITY: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.PTM: Conjugated to ATG12; which is essential for autophagy, but is not required for association with isolation membrane.SIMILARITY: SwissProt: Q9H1Y0 ## Belongs to the ATG5 family. View All» Brand Family: Chemicon View All» Product Name: Anti-APG5 Antibody | AB15404P View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 500 µg View All» Format: Purified View All» Host: Rabbit View All»
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