货号：AB1528

品牌：Merck Millipore

规格：250UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Nerve Growth Factor-β Antibody | AB1528 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Nerve growth factor-beta (NGF). Less than 1% cross-reactivity against recombinant human NT4 and BDNF and approximately 2% for NT3 by ELISA. View All» Immunogen: Mouse nerve growth factor-beta purified from salivary glands. View All» Species Reactivity:

• Chicken

• Human

• Mouse

• Rat
  View All» Non-Reactive Species: Bovine View All» Application Notes: Immunohistochemistry at 1:500-1:5,000 (see suggested protocol). Immunoblotting at 1:500-1:5,000. ELISA at 1:500-1:5,000. Inhibition of biological activity in vitro at 1:10-1:50. BIOLOGICAL ACTIVITY: Neutralizes NGF, but not other neurotrophins. Use neat for in vivo animal studies (5-10 μL/g body weight). Optimal working dilutions must be determined by end user. View All» Presentation: Whole sheep antisera. Lyophilized. Reconstitute with 250 μL of sterile distilled water. View All» Storage Conditions: Maintain at -20°C to -70°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P01138 View All» Entrez Gene Number: NM_002506.2 View All» Gene Symbol:
  • NGFB

  • MGC161426

  • HSAN5

  • NGF

  • Beta-NGF

  • MGC161428
    View All» Alternate Names: NGFbeta View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Western Blotting

    • Immunohistochemistry

    • Affects Function
      View All» Entrez Gene Summary: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. View All» UniProt Summary: FUNCTION: SwissProt: P01138 # Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons.SIZE: 241 amino acids; 26959 Da SUBUNIT: Homodimer.SUBCELLULAR LOCATION: Secreted.DISEASE: SwissProt: P01138 # Defects in NGFB are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. Hereditary sensory and autonomic neuropathies are characterized by loss of pain sensation in combination with other sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self- mutilation. The autonomic involvement is variable.SIMILARITY: SwissProt: P01138 ## Belongs to the NGF-beta family. View All» Brand Family: Chemicon View All» Product Name: Anti-Nerve Growth Factor-β Antibody | AB1528 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 250 µL View All» Format: Serum View All» Host: Sheep View All»
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