货号：AB15097

品牌：Merck Millipore

规格：50Ug

目录价：￥4967.00

市场价格：￥4221.95

会员价格：￥3973.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-mGluR4 Antibody | AB15097 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Cat. # AB15097 recognizes mGluR4 (GRM4). View All» Molecular Weight: ~101 kDa View All» Immunogen: Recombinant Protein. View All» Background Information: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. View All» Species Reactivity:

• Mouse

• Rat
  View All» Species Reactivity Note: Mouse and Rat. Reactivity with other species has not been determined. View All» Control: Mouse Brain Lysate. View All» Quality Assurance: Western Blot:Mouse Brain Lysate. View All» Purification Method: Antigen affinity purified View All» Presentation: Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3. View All» Storage Conditions: Stable for 1 year at 2-8ºC from date of receipt. View All» UniProt Number: Q68EF4 View All» Entrez Gene Number: NP_001013403.1 View All» Gene Symbol:
  • GPRC1D

  • MGLUR4

  • mGlu4

  • mGluR4
    View All» Alternate Names:
    • glutamate metabotropic receptor 4

    • glutamate receptor, metabotropic 4
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity By similarity.SUBUNIT STRUCTURE: Interacts with PICK1 By similarity.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 3 family. View All» Product Name: Anti-mGluR4 Antibody | AB15097 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Purified View All» Host: Rabbit View All»
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