货号：AB15076

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Ephrin Receptor B2 Antibody | AB15076 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Ephrin Receptor B2. By Western blot the antibody recognizes a doublet band at ~90-118 kDa in adult rat brain lysate. View All» Molecular Weight: ~90-118kDa View All» Immunogen: Synthetic peptide. View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:500-1:2,000 on adult rat brain lysate. Optimal working dilutions must be determined by the end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Liquid in PBS with 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: P29323 View All» Entrez Gene Number:

• NM_004442.6

• NM_017449.3
  View All» Gene Symbol:
  • EPHB2

  • EphB2

  • CAPB

  • EPHT3

  • Hek5

  • DRT

  • EPTH3

  • TYRO5

  • ERK

  • HEK5

  • MGC87492

  • PCBC

  • Tyro5
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. View All» UniProt Summary: FUNCTION: SwissProt: P29323 # Receptor for members of the ephrin-B family. Acts as a tumor suppressor.SIZE: 1055 amino acids; 117493 Da SUBUNIT: The ligand-activated form interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. Binds RASGAP through the juxtamembrane tyrosines residues. Interacts with PRKCABP and GRIP1 (By similarity).SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.TISSUE SPECIFICITY: Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.DISEASE:SwissProt: P29323 # Defects in EPHB2 are involved in the progression of prostate cancer [MIM:176807]. & Defects in EPHB2 are involved in the development of prostate cancer metastasis to the brain [MIM:603688].SIMILARITY: SwissProt: P29323 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Ephrin Receptor B2 Antibody | AB15076 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Plasma membrane View All» Format: Affinity Purified View All» Host: Rabbit View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://16ao.com/thread-151974.htm
    © Merck Millipore代理AB15076 EPHRIN REC B2, RBX-100ug;已停产，产品报价联系微信jinshanbio