货号：AB15075

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Ephrin B1 Antibody | AB15075 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Ephrin B1. By Western blot the antibody recognizes a band at ~38 kDa in mouse brain lysate. View All» Molecular Weight: 38 kDa View All» Immunogen: Synthetic peptide. View All» Species Reactivity: Mouse View All» Application Notes: Western blot: 1-5 μg/mL on extracts from mouse brain lysate. Optimal working dilutions must be determined by the end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS with 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: P52795 View All» Entrez Gene Number: NM_004441.3 View All» Gene Symbol:

• EPHB1

• NET

• Elk

• FLJ37986

• Hek6

• ELK

• EphB1

• EPHT2

• HEK6
  View All» Alternate Names: EphB1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. View All» UniProt Summary: FUNCTION: SwissProt: P54762 # Receptor for members of the ephrin-B family. Binds to ephrin-B1, -B2 and -B3. May be involved in cell-cell interactions in the nervous system.SIZE: 984 amino acids; 109885 Da SUBUNIT: The ligand-activated form interacts with GRB2, GRB10 and NCK through their respective SH2 domains. The GRB10 SH2 domain binds EPHB1 through Tyr-928, while GRB2 binds residues within the catalytic domain. The NCK SH2 domain binds EPHB1 through Tyr-594. Interacts with PRKCABP (By similarity).SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.TISSUE SPECIFICITY: Preferentially expressed in brain.SIMILARITY: SwissProt: P54762 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Ephrin B1 Antibody | AB15075 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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