货号：AB15067

品牌：Merck Millipore

规格：EA

目录价：￥3662.00

市场价格：￥3112.70

会员价格：￥2929.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-EMX1 Antibody | AB15067 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptided selected from human EMX1. View All» Molecular Weight: 30 kDa View All» Epitope: C-terminus View All» Immunogen: Synthetic human EMX1 peptide, a.a. 274-290 View All» Background Information: EMX1 and EMX2 are human homologs to the Drosophila developmental genes empty spiracles, and are specifically expressed in the developing telencephalic cortex. During the process of proliferation, migration, differentiation, and maturation, it has been reported that, while EMX2 is expressed in the dorsal telencephalon and small diencephalic regions, EMX1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon and remains localized in most cells of the cerebral cortex. Since EMX1 is expressed in both proliferating and differentiating neurons in the developing embryonic brain, it has also been shown to be a reliable marker of the embryonic pyramidal cell lineages. View All» Species Reactivity: Human View All» Species Reactivity Note: Reacts with human. Comparison of sequence homology suggests that this antibody may also react with mouse, rat, canine, bovine, and equine; however, reactivity with other species has not been tested. View All» Application Notes: Western Blotting: Recommended working dilutions are 1:250 – 1: 500. View All» Control: Human fetal brain lysates. View All» Quality Assurance: Routinely evaluated by Western blot on human fetal brain lysates. View All» Purification Method: Peptide affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing PBS with 0.09% sodium azide. View All» Storage Conditions: Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles. View All» UniProt Number: Q04741 View All» Entrez Gene Number: NM_004097.2 View All» Gene Symbol: EMX1 View All» Alternate Names:

• Empty spiracles homolog 1

• Empty spiracles-like protein 1

• empty spiracles homeobox 1

• empty spiracles homolog 1 (Drosophila)
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. SUBCELLULAR LOCATION: Nucleus (Probable). TISSUE SPECIFICITY: Cerebral cortex. SIMILARITY: Belongs to the EMX homeobox family. SIMILARITY: Contains 1 homeobox DNA-binding domain. View All» Product Name: Anti-EMX1 Antibody | AB15067 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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