货号：AB1479P

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Monocyte Chemotactic Protein-2 Antibody | AB1479P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with human Monocyte/Macrophage Chemotactic Protein-2 (MCP-2). MCP-2 plays an important role in the inflammatory response of blood monocytes and tissues macrophages. View All» Immunogen: Highly pure (>98%) recombinant human MCP-2 View All» Species Reactivity: Human View All» Application Notes: ELISA: A concentration of at least 0.5μg/ml (100μL/well) of AB1479P is required to detect 0.2 - 0.4 ng/well of recombinant MCP-2. Western Blot: A concentration of 0.1 - 0.2 μg/ml of AB1479P is required to detect 1.5 - 3.0 ng/lane of MCP-2, under either reducing or non-reducing conditions. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. A sterile filtered antibody solution (1mg/ml) was lyophilized from 0.5X PBS, pH 7.4. Reconstitute with sterile distilled water. View All» Storage Conditions: The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile water to a concentration of >0.2 mg/ml the antibody is stable for at least six weeks at 2-4ºC. View All» UniProt Number: P80075 View All» Entrez Gene Number: NM_005623.2 View All» Gene Symbol:

• CCL8

• HC14

• SCYA8

• MCP-2

• SCYA10

• MCP2
  View All» Alternate Names: MCP-2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting
    View All» Entrez Gene Summary: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. View All» UniProt Summary: FUNCTION: SwissProt: P80075 # Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.SIZE: 99 amino acids; 11246 Da SUBUNIT: Monomer or homodimer; in equilibrium.SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.PTM: N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.SIMILARITY: SwissProt: P80075 ## Belongs to the intercrine beta (chemokine CC) family. View All» Brand Family: Chemicon View All» Product Name: Anti-Monocyte Chemotactic Protein-2 Antibody | AB1479P View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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