金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:ELISA Development Kit Assay Length:4 hours 40 minutes (after plate preparation) Sample Type & Volume Required:100 µL Sufficient Materials:For fifteen 96-well plates* Range:31.2 - 2,000 pg/mL Specificity:Please see the product datasheet Molecule Information: CEACAM-5/CD66e Long Name: Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 Aliases: CD66e; CEA Entrez Gene IDs: 1048 (Human) Background: CEACAM-5

CEACAM-5 is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumors. This is consistent with a role in the development and maintenance of epithelial architecture. CEACAM-5 is upregulated in a wide variety of human tumors and is a commonly used cancer marker. It promotes tumor cell migration, invasion, adhesion, and metastasis. CEACAM-5 also contributes to tumor formation by maintaining cellular proliferation in the presence of differentiation stimuli, and by blocking apoptosis following loss of ECM anchorage (anoikis).