货号:4500-0455
品牌:Merck Millipore
规格:
目录价:¥20543.00
市场价格:¥17461.55
会员价格:¥16434.40
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Description:
Guava Nexin Reagent
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Trade Name:
Guava
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Qty/Pk:
500 Tests
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Product Overview:
The Guava Nexin® Annexin V Assay offers a simple, reproducible, and reliable assessment of early apoptosis. The assay relies on the translocation of phosphatidyl serine (PS) to the outer surface of the cell membrane, an event often associated with the onset of apoptosis. Simple, sensitive, and reproducible A mix-and-read assay for monitoring externalization of PS through the binding of Annexin V to the exposed PS, the automated single-cell analysis assay is the choice for monitoring apoptosis due to its sensitivity and reproducibility. Annexin V is a calcium-dependent phospholipid binding protein with high affinity for phosphatidylserine (PS), a membrane component normally localized to the internal face of the cell membrane. Early in the apoptotic pathway, molecules of PS are translocated to the outer surface of the cell membrane where Annexin V can readily bind to them.Two-dye strategyThe assay relies on a two-dye stategy: 1) Annexin V-PE to detect PS on the external membrane of apoptotic cells and 2) 7-AAD, a cell impermeant dye, as an indicator of membrane structural integrity. 7-AAD is excluded from live, healthy cells and early apoptotic cells, but permeates late-stage apoptotic and dead cells. For use with all instruments. Click here for more information regarding Instrument Compatibility.
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Components:
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Annexin V-PE
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7-AAD
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Robust Protocol
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Product Name:
Guava Nexin Reagent
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Flow Cytometry Software Type:
Assay Specific Module
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Flow Cytometry Market:
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Bioprocess
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Research
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Flow Cytometry Research Subcategory:
Early
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