金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:Solid Phase Sandwich ELISA Format:96-well strip plate Assay Length:4.5 hours Sample Type & Volume Required Per Well:Cell Culture Supernates (50 µL), Cell Lysates (25 µL), Serum (50 µL), EDTA Plasma (50 µL), Heparin Plasma (50 µL), Human Milk (25 µL) Sensitivity:0.134 ng/mL Assay Range:0.313 - 20 ng/mL (Serum, Heparin Plasma, Cell Culture Supernates, Human Milk, Cell Lysates, EDTA Plasma) Specificity:Natural and recombinant human Semaphorin 3E Cross-reactivity: Interference:No significant interference observed with available related molecules. Molecule Information: Semaphorin 3E Aliases: Sema3E; SEMAH Entrez Gene IDs: 9723 (Human); 20349 (Mouse) Background: Semaphorins The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates). Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved ~400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.