货号：23-034M

品牌：Merck Millipore

规格：1EA

目录价：￥41896.04

市场价格：￥35611.63

会员价格：￥33516.83

金山科研平台，产品价格货期咨询微信：jinshanbio Description: p53 View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Background Information: p53 is expressed in a wide variety of tissues and plays a major role in preventing tumour development. It is involved in cell cycle regulation, functioning as a trans-activator to negatively regulate cell division by controlling a set of genes required for this process. It acts as a tumour suppressor in many tumour types by stimulating either apoptosis or growth arrest depending on the physiological circumstances and the cell type. Defects in p53 expression have been implicated in several diseases including; choroid plexus papilloma, lung cancer, head/neck squamous cell carcinomas, oesophageal squamous cell carcinoma, Li-Fraumeni syndrome, and hereditary adrenocortical carcinoma. View All» Key Applications: Enzyme Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Human View All» Cascade Component: Substrate View All» Brand Family: Upstate View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Long Description: N-terminal c-Myc, 6His-tagged, recombinant human p53 full length, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography. View All» Product Name: p53 View All» Entrez Gene Number: BC003596 (GenBank Number) View All» Alternate Names:

• Cellular tumour antigen p53

• Antigen NY-CO-13

• Phosphoprotein p53

• Tumour suppressor p53

• TP53
  View All» Purification Method: Purified using immobilized metal affinity chromatography. View All»
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