货号：23-027

品牌：Merck Millipore

规格：10Ug

目录价：￥7971.00

市场价格：￥6775.35

会员价格：￥6376.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: b-catenin, activated View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Background Information: β-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion complex, regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that governs cell fate in early embryogenesis. The regulation of β-catenin turnover in the cells is governed by its phosphorylation status which allows the targeting of ubiquitin-dependent proteolysis. Altered levels of protein expression as well as genetic mutations of β-catenin have been implicated in a number of human cancers. View All» Key Applications: Enzyme Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Human View All» Cascade Component: Substrate View All» Brand Family: Upstate View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Long Description: N-terminal c-Myc, 6His-tagged, recombinant human β-catenin full length, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography. Phosphorylated in vitro using GSK-3a (Item # 14-492). View All» Product Name: b-catenin, activated View All» Entrez Gene Number: NM_001904 (GenBank Number) View All» Alternate Names: Catenin beta-1 View All» Purification Method: Purified using immobilized metal affinity chromatography. View All»