金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Paxillin Aliases: PXN Entrez Gene IDs: 5829 (Human); 19303 (Mouse); 360820 (Rat) Background: Paxillin Paxillin is a 65 kDa cytoskeletal adaptor protein and member of the Paxillin family. Paxillin is found at the interface between actin filaments and the plasma membrane, and it localizes to focal adhesions, where it provides a platform for the integration and coordination of adhesion- and growth factor-related signals. Paxillin phosphorylation at tyrosines 31 and 118 is required for integrin-mediated cytoskeletal reorganization, and may play a role in the disassembly of focal adhesions and stress fibers during cellular transformation.