金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: CD300c/LMIR2 Long Name: Leukocyte Mono Ig-like Receptor 2 Aliases: CD300c; CLM6; CMRF-35A; DIgR1; IGSF16; IGSF7; LIR; LMIR2; MAIR-II Entrez Gene IDs: 10871 (Human); 387565 (Mouse) Background: CD300/LMIRs The CD300, alternately designated the LMIR family, contains six to eight type I membrane proteins expressed mainly on cells of the myeloid lineage. Each has a single extracellular V-type Ig-like domain. Some have cytoplasmic ITIM motifs that result in the delivery of an inhibitory signal; others can interact with ITAM motifs and function as activating receptors. Human CD300 proteins have also been designated IREM (immune receptor expressed by myeloid cells) or CMRF-35 for the original identifying antibody; mouse CD300 proteins have alternate naming as CLM (CMRF-35-like molecules).