货号：14-919-K

品牌：Merck Millipore

规格：

目录价：￥410.00

市场价格：￥348.50

会员价格：￥328.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: LRRK2, active View All» Qty/Pk: Bulk View All» Product Overview: This protein is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Human View All» Molecular Weight: 180 kDa View All» Brand Family: Upstate View All» Source: N-terminal FLAG-tagged, recombinant, human LRRK2 amino acids 970-end, expressed by baculovirus in Sf21 insect cells. View All» Presentation: 50mM Tris/HCl pH7.4, 300mM NaCl, 20mM β-glycerophosphate, 0.25mM sodium orthovanadate, 10mM NaF, 150µg/ml FLAG peptide, 20% v/v glycerol, 1mM benzamidine, 0.2mM PMSF, 5mM DTT. Frozen solution. View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: TKL View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• LRRK2

• PARK8

• RIPK7

• ROCO2

• AURA17

• DARDARIN
  View All» Product Name: LRRK2, active View All» Quality Assurance: Routinely evaluated by phosphorylation of ERMtide (RLGRDKYKTLRQIRQ) View All» UniProt Number: Q5S007 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10μg size as catalog # 14-919 and in 250 μg as catalog # 14-919M. View All» Entrez Gene Number: BC117180 View All» Purification Method: Immunoaffinity chromatography. View All»
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