货号：14-731M

品牌：Merck Millipore

规格：1ea

目录价：￥42566.00

市场价格：￥36181.10

会员价格：￥34052.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: CaM Kinase Iδ, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, human, full length CaM Kinase Iδ. View All» Key Applications: Enzyme Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. The encoded protein may be involved in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. View All» UniProt Summary: FUNCTION: SwissProt: Q8IU85 # Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.SIZE: 385 amino acids; 42914 Da SUBCELLULAR LOCATION: Cytoplasm (Probable). Nucleus (Probable). Note=Predominantly cytoplasmic (Probable). Also nuclear upon activation (Probable).TISSUE SPECIFICITY: Broadly expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.DOMAIN:SwissProt: Q8IU85 The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate (By similarity).SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 46.7kDa View All» Brand Family: Upstate View All» Source: Recombinant human protein expressed by baculovirus in Sf21 cells. View All» Presentation: Presented as a frozen liquid in 50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. View All» Protein Target: CaMKIδ View All» Storage Conditions: Stable for 6 months at -70°C from date of shipment. Upon first use, rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70deg;C. View All» Target Sub-Family: CAMK View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• CAMK1D

• CaM-K1

• CaMKI-delta

• Camk1D

• CKLiK

• OTTHUMP00000045030

• CaMKID
  View All» Product Name: CaM Kinase Iδ, active View All» Alternate Names:
  • Calcium/calmodulin-dependent protein kinase type 1D

  • CaMKI-delta
    View All» Concentration: For concentration, please refer to the Certificate of Analysis for individual lots of this enzyme. View All» Quality Assurance: Routinely evaluated by phosphorylation of 150μM KKLRRTLSVA. View All» UniProt Number: Q8IU85 View All» Specific Activity: For Specific Activity data, please refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 20 μg size (cat#14-731) and in bulk (cat# 14-731-K). View All» Entrez Gene Number:
    • NM_020397.2

    • NM_153498.2
      View All» Purity: For purity information, please refer to the Certificate of Analysis for individual lots of this enzyme. View All» Purification Method: Ni²⁺/NTA-agarose View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-145713.htm
      © Merck Millipore代理14-731M CaM Kinase Iδ Protein, active, 20 µg;store at -80℃，产品报价联系微信jinshanbio