货号：14-686

品牌：Merck Millipore

规格：

目录价：￥4733.00

市场价格：￥4023.05

会员价格：￥3786.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: LOK, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Product Overview: N-terminal 6His-tagged, recombinant human LOK amino acids 1-348 View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. View All» UniProt Summary: FUNCTION: SwissProt: O94804 # Can act on substrates such as myelin basic protein and histone 2A on serine and threonine residues (By similarity).SIZE: 968 amino acids; 112135 Da TISSUE SPECIFICITY: Expressed predominantly in lymphoid organs.PTM: Autophosphorylated (By similarity).SIMILARITY: SwissProt: O94804 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 43.2kDa View All» Brand Family: Upstate View All» Source: expressed by baculovirus in Sf21 cells View All» Protein Target: LOK View All» Storage Conditions: stable 6 months at -70°C from date of shipment View All» Target Sub-Family: STE View All» Gene Symbol:

• STK10

• PRO2729

• LOK
  View All» Product Name: LOK, active View All» Quality Assurance: routinely evaluated by phosphorylation of Axltide (Catalog# 12-516) View All» UniProt Number: O94804 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Entrez Gene Number: NM_005990.3 View All» Purification Method: Ni²⁺/NTA-agarose View All»
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