货号：14-676

品牌：Merck Millipore

规格：1EA

目录价：￥5959.62

市场价格：￥5065.68

会员价格：￥4767.70

金山科研平台，产品价格货期咨询微信：jinshanbio Description: NLK, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, human NLK, amino acids 121-end View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: Q9UBE8 # Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta- catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (By similarity).COFACTOR: Magnesium (By similarity).SIZE: 515 amino acids; 57048 Da SUBUNIT: Interacts with HIPK2 and MYB.SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity). Note=Predominantly nuclear. A smaller fraction is cytoplasmic (By similarity).PTM: Dually phosphorylated on Thr-291 and Tyr-293, which activates the enzyme (By similarity).SIMILARITY: SwissProt: Q9UBE8 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 48.7kDa View All» Brand Family: Upstate View All» Source: expressed by baculovirus in Sf21 cells View All» Protein Target: NLK View All» Storage Conditions: Stable for 6 months at -70°C from date of shipment View All» Target Sub-Family: CMGC View All» Gene Symbol:

• NLK

• DKFZp761G1211

• FLJ21033

• LAK1
  View All» Product Name: NLK, active View All» Quality Assurance: routinely evaluated by phosphorylation of myelin basic protein (Catalog # 13-104) View All» UniProt Number: Q9UBE8 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Entrez Gene Number: NM_016231.4 View All» Purification Method: Ni²⁺/NTA-agarose View All»
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  © Merck Millipore代理14-676 NLK Protein, active, 10 µg，产品报价联系微信jinshanbio