金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: IFN-gamma R1/CD119 Long Name: Interferon gamma Receptor 1 Aliases: CD119; IFNGR1 Entrez Gene IDs: 3459 (Human); 15979 (Mouse) Background: IFN-gamma R1/CD119 The high-affinity IFN-gamma receptor complex is made up of two type I transmembrane proteins, IFN-gamma R1 (IFN-gamma R alpha) and IFN-gamma R2 (IFN-gamma R beta). Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for IFN-gamma signaling, but does not bind IFN-gamma by itself.