金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: JAB1 Long Name: Jun Activation Domain-binding Protein 1 Aliases: COPS5; CSN5; MOV-34; SGN5 Entrez Gene IDs: 10987 (Human); 26754 (Mouse); 312916 (Rat) Background: JAB1 JAB1 (Jun activation domain binding protein-1), also called COPS5 or CSN5 (COP9 signalosome-5), is a 334 amino acid, 38 kDa protein that is a subunit of the COP9 signalosome complex. It mediates cytosolic translocation of the cell cycle inhibitory protein, CDKN1B/p27Kip1, for degradation, thus promoting proliferation. It is widely expressed, especially in proliferating cells, and upregulates granulopoiesis when overexpressed.