R&D Systems代理AF6165 Human/Mouse FoxO3 Affinity Purified Polyclonal Ab (100 UG)-试剂-金山科研平台

R&D Systems代理AF6165 Human/Mouse FoxO3 Affinity Purified Polyclonal Ab (100 UG)

2025-06-28

货号：AF6165

品牌：R&D Systems

规格：100ug

目录价：￥5180.00

市场价格：￥4144.00

会员价格：￥4144.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: FoxO3 Long Name: Forkhead Box O3 Aliases: AF6q21; FKHRL1; FKHRL1P2; FOXO3A Entrez Gene IDs: 2309 (Human); 56484 (Mouse); 294515 (Rat) Background: FoxO3

View FoxO3 IHC images. Forkhead box O3 (FoxO3) is a ubiquitously expressed 72 kDa transcriptional regulator that is involved in cellular differentiation, angiogenesis, tumor progression, apoptosis, and the responses to oxidative stress and DNA damage. Phosphorylation of FoxO3 by Akt induces its association with 14-3-3 proteins and its retention in the cytoplasm. In response to the loss of survival factors, dephosphorylation of FoxO3 induces its translocation to the nucleus where it promotes apoptosis. Its level of acetylation is regulated in response to cellular metabolic requirements.

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